I put this on a Fender Player Series Stratocaster from 2018 (MIM).
No matter if your Player Series Strat is in SSS or HSS configuration, it will fit without additional work, as they route all the Player Series Strat bodies for H-S-H configuration. You will need a new pickguard, even if your Player series Strat is in HSS config. as the Fender pickup has 3 screws and this one only has 2 (don't let the pictures fool you, it's not the same as the Fender pickup).
Sound wise, this is great sounding humbucker, but if you don't want it to sound too flat, consider also changing the pots from 250K to 500K.