I own 2 of these cases. One holds Arturia Keylab 88, and the other Novation Impulse 61 + audio interface and accessories. They are used 3-4 times a week for gigs all over the country.
Lifting and moving them around isn't hard, they are fairly light and the handles seem pretty solid. Wheels make the job much easier without sacrificing any van space with their positioning. The case is bulky of course, but it seems compact enough and without any wasted space.
The interior is nice and soft, you can re-arrange any inserts to your liking,(there are 4 types of them) which have convenient velcros attached. There are also small velcros strips, which I personally use to strap any spare cables.
I have no doubts about the durability of these cases so far, but the real problem I noticed is heat and direct sunlight. I left one of the cases in intense heat in my SUV in those conditions for and hour and when I got back I found it slightly deformed. Forming sort of a bubble on the main wall. Once I opened the car doors and gently pressed on the bubble and it cooled down it went to its normal shape without any trace. The equipment inside suffered no damage. I suppose there is a warning about it somewhere in case's documentation or on Gator's website, so I won't hold it against them. It is plastic after all and nothing's fully fool-proof.
To sum up - if you are in search for good looking, compact, proper hardcase with highly customizable, modular interior, this model deserves a closer look!